Regional
FirstHealth of the Carolinas
FirstHealth of the Carolinas (NC) carries 37 drugs across 170 dose entries in its current published protocol, effective 2025-09-01.
Drugs and doses37
Adenosine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Narrow-complex tachycardia | adult | 12 mg | IV/IO | not captured | standing | page 23 |
| Narrow-complex tachycardia | peds | 0.1 mg/kg | IV/IO | not captured | standing | page 23 |
Albuterol
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Allergic reaction | adult | 5 mg | NEB | not captured | standing | page 46 |
| Allergic reaction | peds | 2.5 mg | NEB | not captured | standing | page 46 |
| Asthma / bronchospasm | adult | 5 mg | NEB | not captured | standing | page 67 |
| Asthma / bronchospasm | peds | 2.5 mg | NEB | not captured | standing | page 67 |
| COPD | adult | 5 mg | NEB | not captured | standing | page 67 |
| Hyperkalemia | adult | 10 mg | NEB | not captured | standing | page 49 |
Amiodarone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Narrow-complex tachycardia | adult | 150 mg | IV/IO | not captured | standing | page 23 |
| VF / pulseless VT | adult | 300 mg | IV/IO | not captured | standing | page 29 |
| VF / pulseless VT | peds | 5 mg/kg | IV/IO | not captured | standing | page 29 |
Aspirin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| ACS / chest pain | adult | 324 mg | PO | not captured | standing | page 19 |
Atropine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Bradycardia | adult | 0.5 mg | IV/IO | not captured | standing | page 15 |
| Bradycardia | peds | 0.02 mg/kg | IV/IO | not captured | standing | page 15 |
| Nerve agent exposure | adult | 2 mg | IV/IO/IM | not captured | standing | page 150 |
| Nerve agent exposure | peds | 0.02 mg/kg | IV/IO/IM | not captured | standing | page 150 |
Calcium Chloride
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Beta-blocker / calcium-channel-blocker overdose | adult | 1 g | IV/IO | not captured | standing | page 148 |
| Beta-blocker / calcium-channel-blocker overdose | adult | 1 g | IV/IO | not captured | standing | page 148 |
| Beta-blocker / calcium-channel-blocker overdose | peds | 20 mg/kg | IV/IO | not captured | standing | page 148 |
| Beta-blocker / calcium-channel-blocker overdose | peds | 20 mg/kg | IV/IO | not captured | standing | page 148 |
| Crush injury | adult | 1 g | IV/IO | not captured | standing | page 123 |
| Crush injury | peds | 20 mg/kg | IV/IO | not captured | standing | page 123 |
| Hyperkalemia | adult | 1 g | IV/IO | not captured | standing | page 49 |
| Hyperkalemia | peds | 20 mg/kg | IV/IO | not captured | standing | page 49 |
Cefazolin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Trauma / hemorrhage | adult | 2 g | IV/IO/IM | not captured | standing | page 125 |
| Trauma / hemorrhage | peds | 30 mg/kg | IV/IO/IM | not captured | standing | page 125 |
Dextrose
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hypoglycemia | adult | 250 mL | IV/IO | not captured | standing | page 48 |
| Hypoglycemia | peds | 2 mL/kg | IV/IO | not captured | standing | page 48 |
Diltiazem
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Narrow-complex tachycardia | adult | 20 mg | IV/IO | not captured | standing | page 23 |
Diphenhydramine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Allergic reaction | adult | 50 mg | PO | not captured | standing | page 46 |
| Allergic reaction | adult | 50 mg | IV/IO/IM | not captured | standing | page 46 |
| Allergic reaction | peds | 1 mg/kg | PO | not captured | standing | page 46 |
| Allergic reaction | peds | 1 mg/kg | IV/IO/IM | not captured | standing | page 46 |
| Anaphylaxis | adult | 50 mg | PO | not captured | standing | page 46 |
| Anaphylaxis | adult | 50 mg | IV/IO/IM | not captured | standing | page 46 |
| Anaphylaxis | peds | 1 mg/kg | PO | not captured | standing | page 46 |
| Anaphylaxis | peds | 1 mg/kg | IV/IO/IM | not captured | standing | page 46 |
| Dystonic reaction | adult | 50 mg | IV/IO/IM/PO | not captured | standing | page 182 |
| Dystonic reaction | peds | 1 mg/kg | IV/IO/IM/PO | not captured | standing | page 182 |
Epinephrine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Allergic reaction | adult | 0.3–0.5 mg | IM | not captured | standing | page 46 |
| Allergic reaction | peds | 0.15 mg | IM | not captured | standing | page 46 |
| Anaphylaxis | adult | 0.3–0.5 mg | IM | not captured | standing | page 46 |
| Anaphylaxis | peds | 0.15 mg | IM | not captured | standing | page 46 |
| Cardiac arrest | adult | 1 mg | IV/IO | not captured | standing | page 13 |
| Cardiac arrest | peds | 0.01 mg/kg | IV/IO | not captured | standing | page 13 |
| COPD | adult | 1 mg | NEB | not captured | standing | page 67 |
| Croup | peds | 1 mg | NEB | not captured | standing | page 73 |
| Hypotension / shock | adult | 10 mcg | IV/IO | not captured | standing | page 31 |
| Hypotension / shock | peds | 1 mcg/kg | IV/IO | not captured | standing | page 31 |
Famotidine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Allergic reaction | adult | 20 mg | IV/IO | not captured | standing | page 46 |
| Allergic reaction | peds | 0.25 mg/kg | IV/IO | not captured | standing | page 46 |
Fentanyl
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| ACS / chest pain | adult | 100 mcg | IV/IO/IM/IN | not captured | standing | page 19 |
| ACS / chest pain | peds | 1 mcg/kg | IV/IO/IM/IN | not captured | standing | page 19 |
| Mild to moderate pain | adult | 50–100 mcg | IV/IO/IM/IN | not captured | standing | page 169 |
| Mild to moderate pain | peds | 0.5 mcg/kg | IV/IO/IM/IN | not captured | standing | page 169 |
| Post-intubation sedation | adult | 100 mcg | IV/IO/IM/IN | not captured | standing | page 75 |
| Post-intubation sedation | peds | 1 mcg/kg | IV/IO/IM/IN | not captured | standing | page 75 |
Glucagon
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Beta-blocker / calcium-channel-blocker overdose | adult | 2–4 mg | IV/IO/IM | not captured | standing | page 148 |
| Beta-blocker / calcium-channel-blocker overdose | adult | 2–4 mg | IV/IO/IM | not captured | standing | page 148 |
| Beta-blocker / calcium-channel-blocker overdose | peds | 0.1 mg/kg | IV/IO/IM | not captured | standing | page 148 |
| Beta-blocker / calcium-channel-blocker overdose | peds | 0.1 mg/kg | IV/IO/IM | not captured | standing | page 148 |
| Hypoglycemia | adult | 1 mg | IM | not captured | standing | page 48 |
| Hypoglycemia | peds | 0.1 mg/kg | IM | not captured | standing | page 48 |
Haloperidol
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Agitation | adult | 2.5 mg | IM | not captured | standing | page 183 |
| Nausea / vomiting | adult | 2.5 mg | IV/IO/IM | not captured | standing | page 157 |
| Nausea / vomiting | adult | 2.5 mg | IV/IO/IM/SQ | not captured | standing | page 112 |
| Other | adult | 2.5 mg | IV/IO/IM | not captured | standing | page 157 |
Heparin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| STEMI | adult | 60 unit/kg | IV/IO | not captured | standing | page 19 |
| STEMI | adult | 60 unit/kg | IV | not captured | standing | page 19 |
Ibuprofen
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Fever | adult | 800 mg | PO | not captured | standing | page 168 |
| Fever | peds | 10 mg/kg | PO | not captured | standing | page 168 |
| Mild to moderate pain | adult | 800 mg | PO | not captured | standing | page 169 |
| Mild to moderate pain | peds | 10 mg/kg | PO | not captured | standing | page 169 |
Ipratropium
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Allergic reaction | adult | 0.5 mg | NEB | not captured | standing | page 46 |
| Allergic reaction | peds | 0.5 mg | NEB | not captured | standing | page 46 |
| Asthma / bronchospasm | adult | 0.5 mg | NEB | not captured | standing | page 67 |
| Asthma / bronchospasm | peds | 0.5 mg | NEB | not captured | standing | page 67 |
| COPD | adult | 0.5 mg | NEB | not captured | standing | page 67 |
Ketamine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hyperactive delirium | adult | 4 mg/kg | IM | not captured | standing | page 185 |
| Mild to moderate pain | adult | 0.3 mg/kg | IV/IO | not captured | standing | page 169 |
| Mild to moderate pain | adult | 0.3 mg/kg | IM | not captured | standing | page 169 |
| Mild to moderate pain | peds | 0.3 mg/kg | IV/IO | not captured | standing | page 169 |
| Mild to moderate pain | peds | 0.3 mg/kg | IM | not captured | standing | page 169 |
| Post-intubation sedation | adult | 3 mg/kg | IV/IO | not captured | standing | page 75 |
| Post-intubation sedation | peds | 3 mg/kg | IV/IO | not captured | standing | page 75 |
Ketorolac
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Fever | adult | 15 mg | IV | not captured | standing | page 168 |
| Fever | adult | 30 mg | IM | not captured | standing | page 168 |
| Fever | peds | 0.5 mg/kg | IV | not captured | standing | page 168 |
| Fever | peds | 0.5 mg/kg | IM | not captured | standing | page 168 |
| Mild to moderate pain | adult | 15 mg | IV | not captured | standing | page 169 |
| Mild to moderate pain | adult | 30 mg | IM | not captured | standing | page 169 |
| Mild to moderate pain | peds | 0.5 mg/kg | IV | not captured | standing | page 169 |
| Mild to moderate pain | peds | 0.5 mg/kg | IM | not captured | standing | page 169 |
Labetalol
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 10 mg | IV/IO | not captured | standing | page 55 |
| Stroke | adult | 10 mg | IV/IO | not captured | standing | page 55 |
Levetiracetam
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Head injury / TBI | adult | 20 mg/kg | IV/IO | not captured | standing | page 126 |
| Head injury / TBI | peds | 20 mg/kg | IV/IO | not captured | standing | page 126 |
| Seizure | adult | 20 mg/kg | IV/IO | not captured | standing | page 61 |
| Seizure | peds | 20 mg/kg | IV/IO | not captured | standing | page 61 |
Lidocaine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Mild to moderate pain | adult | 20 mg | IV/IO | not captured | standing | page 277 |
| Mild to moderate pain | peds | 0.5 mg/kg | IV/IO | not captured | standing | page 277 |
| Wide-complex tachycardia | adult | 1 mg/kg | IV/IO | not captured | standing | page 27 |
| VF / pulseless VT | adult | 1–1.5 mg/kg | IV/IO | not captured | standing | page 29 |
| VF / pulseless VT | adult | 1–1.5 mg/kg | IV/IO | not captured | standing | page 29 |
| VF / pulseless VT | peds | 1 mg/kg | IV/IO | not captured | standing | page 29 |
| VF / pulseless VT | peds | 1 mg/kg | IV/IO | not captured | standing | page 29 |
Magnesium Sulfate
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Asthma / bronchospasm | adult | 2 g | IV/IO | not captured | standing | page 67 |
| Asthma / bronchospasm | peds | 40 mg/kg | IV/IO | not captured | standing | page 67 |
| Wide-complex tachycardia | adult | 2 g | IV/IO | not captured | standing | page 27 |
| Wide-complex tachycardia | peds | 40 mg/kg | IV/IO | not captured | standing | page 27 |
| VF / pulseless VT | adult | 2 g | IV/IO | not captured | standing | page 29 |
| VF / pulseless VT | adult | 2 g | IV/IO | not captured | standing | page 29 |
| VF / pulseless VT | peds | 40 mg/kg | IV/IO | not captured | standing | page 29 |
| VF / pulseless VT | peds | 40 mg/kg | IV/IO | not captured | standing | page 29 |
Methylprednisolone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Adrenal crisis | adult | 125 mg | IV/IO/IM | not captured | standing | page 54 |
| Allergic reaction | adult | 125 mg | IV/IO/IM | not captured | standing | page 46 |
| Allergic reaction | peds | 2 mg/kg | IV/IO/IM | not captured | standing | page 46 |
| Asthma / bronchospasm | adult | 125 mg | IV/IO/IM | not captured | standing | page 67 |
| Asthma / bronchospasm | peds | 2 mg/kg | IV/IO/IM | not captured | standing | page 67 |
| COPD | adult | 125 mg | IV/IO/IM | not captured | standing | page 67 |
| Other | adult | 125 mg | IV/IO/IM | not captured | standing | page 54 |
Midazolam
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Agitation | adult | 2.5 mg | IV/IO/IN | not captured | standing | page 183 |
| Agitation | adult | 5 mg | IM | not captured | standing | page 183 |
| Agitation | peds | 0.2 mg/kg | IV/IO/IN | not captured | standing | page 183 |
| Agitation | peds | 0.2 mg/kg | IM | not captured | standing | page 183 |
| Bradycardia | adult | 2.5 mg | IV/IO/IM/IN | not captured | standing | page 15 |
| Bradycardia | peds | 0.2 mg/kg | IV/IO/IM/IN | not captured | standing | page 15 |
| Hyperactive delirium | adult | 5 mg | IM | not captured | standing | page 185 |
| Hyperactive delirium | peds | 0.2 mg/kg | IM | not captured | standing | page 185 |
| Seizure | adult | 10 mg | IM | not captured | standing | page 173 |
| Seizure | adult | 2.5 mg | IV/IO | not captured | standing | page 173 |
| Seizure | peds | 0.2 mg/kg | IV/IO | not captured | standing | page 173 |
| Seizure | peds | 0.2 mg/kg | IM | not captured | standing | page 173 |
| Narrow-complex tachycardia | adult | 2.5 mg | IV/IO/IM/IN | not captured | standing | page 23 |
| Narrow-complex tachycardia | peds | 0.2 mg/kg | IV/IO/IM/IN | not captured | standing | page 23 |
| Wide-complex tachycardia | adult | 2.5 mg | IV/IO/IM/IN | not captured | standing | page 27 |
Morphine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| ACS / chest pain | adult | 2–4 mg | IV/IO/IM | not captured | standing | page 19 |
| Mild to moderate pain | adult | 2–4 mg | IV/IO/IM | not captured | standing | page 169 |
| Mild to moderate pain | peds | 0.1 mg/kg | IV/IO/IM | not captured | standing | page 169 |
Nitroglycerin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| ACS / chest pain | adult | 0.4 mg | SL | not captured | standing | page 19 |
| ACS / chest pain | adult | 1–2 inch | TD | not captured | standing | page 19 |
| CHF / pulmonary edema | adult | 0.4 mg | SL | not captured | standing | page 21 |
Norepinephrine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Bradycardia | peds | 0.1–2 mcg/kg | IV/IO | not captured | standing | page 84 |
| Hypotension / shock | adult | 4–30 mcg | IV/IO | not captured | standing | page 31 |
| Hypotension / shock | adult | 4–30 mcg | IV/IO | not captured | standing | page 31 |
| Hypotension / shock | peds | 0.1–2 mcg/kg | IV/IO | not captured | standing | page 31 |
| Hypotension / shock | peds | 0.1–2 mcg/kg | IV/IO | not captured | standing | page 31 |
| Sepsis | adult | 4–30 mcg | IV/IO | not captured | standing | page 31 |
| Sepsis | peds | 0.1–2 mcg/kg | IV/IO | not captured | standing | page 31 |
Ondansetron
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Nausea / vomiting | adult | 4 mg | IV/IO/IM/PO/ODT | not captured | standing | page 156 |
| Nausea / vomiting | adult | 4 mg | IV/IO/IM/PO/ODT | not captured | standing | page 156 |
| Nausea / vomiting | peds | 0.2 mg/kg | IV/IO/IM/PO/ODT | not captured | standing | page 156 |
| Nausea / vomiting | peds | 0.2 mg/kg | IV/IO/IM/PO/ODT | not captured | standing | page 156 |
Oral Glucose
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hypoglycemia | adult | 15 g | PO | not captured | standing | page 156 |
| Hypoglycemia | peds | 1/2 to 1 Pack | PO | not captured | standing | page 156 |
Oxymetazoline
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 2 spray | not captured | not captured | standing | page 167 |
| Other | peds | 2 spray | not captured | not captured | standing | page 167 |
Oxytocin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Obstetric hemorrhage | adult | 10 unit | IM | not captured | standing | page 57 |
| Other | adult | 10 unit | IM | not captured | standing | page 57 |
Procainamide
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Wide-complex tachycardia | adult | 40 mg | IV/IO | not captured | standing | page 25 |
Promethazine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Nausea / vomiting | adult | 12.5 mg | IM/PO | not captured | standing | page 156 |
Sodium Bicarbonate
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Crush injury | adult | 50 mEq | IV/IO | not captured | standing | page 123 |
| Crush injury | peds | 1 mEq/kg | IV/IO | not captured | standing | page 123 |
| Hyperkalemia | adult | 50 mEq | IV | not captured | standing | page 49 |
| Hyperkalemia | peds | 1 mEq/kg | IV | not captured | standing | page 49 |
| Tricyclic overdose | adult | 50 mEq | IV/IO | not captured | standing | page 148 |
| Tricyclic overdose | peds | 1 mEq/kg | IV/IO | not captured | standing | page 148 |
Tranexamic Acid
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Obstetric hemorrhage | adult | 2 g | IV/IO | not captured | standing | page 58 |
| Other | adult | 500 mg | TOP | not captured | standing | page 167 |
| Trauma / hemorrhage | adult | 1 g | IV/IO | not captured | standing | page 128 |