Statewide
Michigan Department of Health and Human Services (MDHHS)
Michigan Department of Health and Human Services (MDHHS) (MI) carries 31 drugs across 155 dose entries in its current published protocol, effective 2025-11-17.
An undated version is under review. The figures below are from the current listed document.
Drugs and doses31
Acetaminophen
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Fever | adult | 650 mg | PO | not captured | not captured | page not captured |
| Fever | adult | weight-based | PO | not captured | not captured | page not captured |
| Fever | peds | weight-based | PO | not captured | not captured | page not captured |
| Mild to moderate pain | adult | 650 mg | PO | not captured | not captured | page not captured |
Adenosine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| SVT | adult | 0.1 mg/kg | IV | not captured | not captured | page not captured |
| SVT | adult | 0.2 mg/kg | IV | not captured | not captured | page not captured |
| SVT | adult | 12 mg | IV | not captured | not captured | page not captured |
| SVT | adult | 6 mg | IV | not captured | not captured | page not captured |
| SVT | peds | 0.1 mg/kg | IV | not captured | not captured | page not captured |
| SVT | peds | 0.2 mg/kg | IV | not captured | not captured | page not captured |
Albuterol
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hyperkalemia | adult | 2.5 mg | NEB | not captured | not captured | page not captured |
| Respiratory distress | adult | 2.5 mg | NEB | not captured | not captured | page not captured |
Aspirin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| ACS / chest pain | adult | 325 mg | PO | not captured | not captured | page not captured |
| ACS / chest pain | adult | 325 mg | PO | not captured | not captured | page not captured |
Atropine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Bradycardia | adult | 0.02 mg/kg | IV/IO | not captured | not captured | page not captured |
| Bradycardia | adult | 1 mg | IV/IO | not captured | not captured | page not captured |
| Bradycardia | peds | 0.02 mg/kg | IV/IO | not captured | not captured | page not captured |
| Nerve agent exposure | adult | 2 mg | IV/IM | not captured | not captured | page not captured |
Calcium Chloride
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Beta-blocker / calcium-channel-blocker overdose | adult | 1 g | IV | not captured | not captured | page not captured |
| Beta-blocker / calcium-channel-blocker overdose | adult | 20 mg/kg | IV | not captured | not captured | page not captured |
| Beta-blocker / calcium-channel-blocker overdose | peds | 20 mg/kg | IV | not captured | not captured | page not captured |
| Cardiac arrest | adult | 1 g | IV/IO | not captured | not captured | page not captured |
| Cardiac arrest | adult | 20 mg/kg | IV/IO | not captured | not captured | page not captured |
| Cardiac arrest | peds | 20 mg/kg | IV/IO | not captured | not captured | page not captured |
| Crush injury | adult | 1 g | IV | not captured | not captured | page not captured |
| Crush injury | adult | 20 mg/kg | IV | not captured | not captured | page not captured |
| Crush injury | peds | 20 mg/kg | IV | not captured | not captured | page not captured |
Cefazolin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 2 g | IV | not captured | not captured | page not captured |
| Other | adult | 30 mg/kg | IV | not captured | not captured | page not captured |
| Other | peds | 30 mg/kg | IV | not captured | not captured | page not captured |
| Trauma / hemorrhage | adult | 2 g | IV | not captured | not captured | page not captured |
| Trauma / hemorrhage | adult | 2 g | IV | not captured | not captured | page not captured |
| Trauma / hemorrhage | adult | 30 mg/kg | IV | not captured | not captured | page not captured |
| Trauma / hemorrhage | adult | 30 mg/kg | IV | not captured | not captured | page not captured |
| Trauma / hemorrhage | peds | 30 mg/kg | IV | not captured | not captured | page not captured |
| Trauma / hemorrhage | peds | 30 mg/kg | IV | not captured | not captured | page not captured |
Ceftriaxone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Trauma / hemorrhage | adult | 2 g | IV | not captured | not captured | page not captured |
| Trauma / hemorrhage | adult | 50 mg/kg | IV | not captured | not captured | page not captured |
| Trauma / hemorrhage | peds | 50 mg/kg | IV | not captured | not captured | page not captured |
Dextrose
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hypoglycemia | adult | 0.5 g/kg | IV | not captured | not captured | page not captured |
| Hypoglycemia | adult | 25 g | IV | not captured | not captured | page not captured |
| Hypoglycemia | peds | 0.5 g/kg | IV | not captured | not captured | page not captured |
Diazepam
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Procedural sedation | adult | 5–10 mg | IV/IO | not captured | not captured | page not captured |
Diphenhydramine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Allergic reaction | adult | 1 mg/kg | IV/IO/IM | not captured | not captured | page not captured |
| Allergic reaction | adult | 50 mg | IV/IO/IM | not captured | not captured | page not captured |
| Allergic reaction | peds | 1 mg/kg | IV/IO/IM | not captured | not captured | page not captured |
| Dystonic reaction | adult | 1 mg/kg | IV | not captured | not captured | page not captured |
| Dystonic reaction | adult | 50 mg | IV | not captured | not captured | page not captured |
| Dystonic reaction | peds | 1 mg/kg | IV | not captured | not captured | page not captured |
| Nausea / vomiting | adult | 1 mg/kg | IV | not captured | not captured | page not captured |
| Nausea / vomiting | adult | 12.5–25 mg | IV/IM | not captured | not captured | page not captured |
| Nausea / vomiting | peds | 1 mg/kg | IV | not captured | not captured | page not captured |
Epinephrine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Anaphylaxis | adult | 0.15 mg | IM | not captured | not captured | page not captured |
| Anaphylaxis | adult | 0.3 mg | IM | not captured | not captured | page not captured |
| Anaphylaxis | peds | 0.15 mg | IM | not captured | not captured | page not captured |
| Bradycardia | peds | 0.01 mg/kg | IV/IO | not captured | not captured | page not captured |
| Cardiac arrest | adult | 0.01 mg/kg | IV/IO | not captured | not captured | page not captured |
| Cardiac arrest | adult | 1 mg | IV/IO | not captured | not captured | page not captured |
| Cardiac arrest | peds | 0.01 mg/kg | IV/IO | not captured | not captured | page not captured |
| Hypotension / shock | adult | 10–20 mcg | IV/IO | not captured | not captured | page not captured |
| Hypotension / shock | peds | 1 mcg/kg | IV/IO | not captured | not captured | page not captured |
| Respiratory distress | adult | 0.15 mg | IM | not captured | not captured | page not captured |
| Respiratory distress | adult | 0.3 mg | IM | not captured | not captured | page not captured |
| Respiratory distress | peds | 0.15 mg | IM | not captured | not captured | page not captured |
Fentanyl
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| ACS / chest pain | adult | 1 mcg/kg | IV/IO/IM/IN | not captured | not captured | page not captured |
| Other | adult | 1 mcg/kg | IV/IO | not captured | not captured | page not captured |
| Other | adult | 50–100 mcg | IV/IO | not captured | not captured | page not captured |
| Other | peds | 1 mcg/kg | IV/IO | not captured | not captured | page not captured |
| Mild to moderate pain | adult | 1 mcg/kg | IV/IO/IM/IN | not captured | not captured | page not captured |
Glucagon
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hypoglycemia | adult | 0.5 mg | IM | not captured | not captured | page not captured |
| Hypoglycemia | adult | 1 mg | IM | not captured | not captured | page not captured |
| Hypoglycemia | adult | 3 mg | IN | not captured | not captured | page not captured |
| Hypoglycemia | peds | 0.5 mg | IM | not captured | not captured | page not captured |
Hydroxocobalamin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Cyanide poisoning | adult | 5 g | IV/IO | not captured | not captured | page not captured |
| Cyanide poisoning | adult | 5 g | IV/IO | not captured | not captured | page not captured |
| Cyanide poisoning | adult | 70 mg/kg | IV/IO | not captured | not captured | page not captured |
| Cyanide poisoning | adult | 70 mg/kg | IV/IO | not captured | not captured | page not captured |
| Cyanide poisoning | peds | 70 mg/kg | IV/IO | not captured | not captured | page not captured |
| Cyanide poisoning | peds | 70 mg/kg | IV/IO | not captured | not captured | page not captured |
Ibuprofen
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Fever | adult | 400 mg | PO | not captured | not captured | page not captured |
| Fever | adult | weight-based | PO | not captured | not captured | page not captured |
| Fever | peds | weight-based | PO | not captured | not captured | page not captured |
| Mild to moderate pain | adult | 400 mg | PO | not captured | not captured | page not captured |
| Mild to moderate pain | adult | weight-based | PO | not captured | not captured | page not captured |
| Mild to moderate pain | peds | weight-based | PO | not captured | not captured | page not captured |
Ipratropium
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Allergic reaction | adult | 500 mcg | NEB | not captured | not captured | page not captured |
| Respiratory distress | adult | 500 mcg | NEB | not captured | not captured | page not captured |
Lidocaine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 0.5 mg/kg | IO | not captured | not captured | page not captured |
| Other | adult | 20 mg | IO | not captured | not captured | page not captured |
| Other | peds | 0.5 mg/kg | IO | not captured | not captured | page not captured |
| Wide-complex tachycardia | adult | 1 mg/kg | IV | not captured | not captured | page not captured |
| Wide-complex tachycardia | adult | 1 mg/kg | IV/IO | not captured | not captured | page not captured |
| Wide-complex tachycardia | peds | 1 mg/kg | IV/IO | not captured | not captured | page not captured |
| VF / pulseless VT | adult | 1 mg/kg | IV/IO | not captured | not captured | page not captured |
Magnesium Sulfate
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Asthma / bronchospasm | adult | 2 g | IV | not captured | not captured | page not captured |
| Cardiac arrest | adult | 2 g | IV/IO | not captured | not captured | page not captured |
| Eclampsia / pre-eclampsia | adult | 4 g | IV/IO | not captured | not captured | page not captured |
Methylprednisolone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Adrenal crisis | adult | 125 mg | IV/IO/IM | not captured | not captured | page not captured |
| Adrenal crisis | adult | 2 mg/kg | IV/IO/IM | not captured | not captured | page not captured |
| Adrenal crisis | peds | 2 mg/kg | IV/IO/IM | not captured | not captured | page not captured |
| Allergic reaction | adult | 125 mg | IV/IO/IM | not captured | not captured | page not captured |
| Allergic reaction | adult | 2 mg/kg | IV/IO/IM | not captured | not captured | page not captured |
| Allergic reaction | peds | 2 mg/kg | IV/IO/IM | not captured | not captured | page not captured |
| Respiratory distress | adult | 125 mg | IV/IO/IM | not captured | not captured | page not captured |
| Respiratory distress | adult | 2 mg/kg | IV/IO/IM | not captured | not captured | page not captured |
| Respiratory distress | peds | 2 mg/kg | IV/IO/IM | not captured | not captured | page not captured |
Midazolam
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hyperactive delirium | adult | 10 mg | IM/IN | not captured | not captured | page not captured |
| Other | adult | 0.1 mg/kg | IM/IN | not captured | not captured | page not captured |
| Other | adult | 0.1 mg/kg | IM | not captured | not captured | page not captured |
| Other | peds | 0.1 mg/kg | IM | not captured | not captured | page not captured |
| Procedural sedation | adult | 0.05 mg/kg | IV/IO | not captured | not captured | page not captured |
| Procedural sedation | adult | 1–5 mg | IV/IO | not captured | not captured | page not captured |
| Procedural sedation | peds | 0.05 mg/kg | IV/IO | not captured | not captured | page not captured |
| Seizure | adult | 0.1 mg/kg | IM | not captured | not captured | page not captured |
| Seizure | adult | 10 mg | IM | not captured | not captured | page not captured |
| Seizure | adult | 5 mg | IV/IO | not captured | not captured | page not captured |
| Seizure | adult | 5 mg | IV/IO/IM/IN | not captured | not captured | page not captured |
| Seizure | peds | 0.05 mg/kg | IV/IO | not captured | not captured | page not captured |
| Seizure | peds | 0.1 mg/kg | IM | not captured | not captured | page not captured |
Naloxone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Cardiac arrest | adult | 2 mg | IV/IO | not captured | not captured | page not captured |
| Cardiac arrest | adult | 2–4 mg | IN | not captured | not captured | page not captured |
| Opioid overdose | adult | 0.1 mg/kg | IM | not captured | not captured | page not captured |
| Opioid overdose | adult | 0.1 mg/kg | IV | not captured | not captured | page not captured |
| Opioid overdose | adult | 0.5 mg | IN | not captured | not captured | page not captured |
| Opioid overdose | adult | 1 mg | IN | not captured | not captured | page not captured |
| Opioid overdose | adult | 1.5 mg | IN | not captured | not captured | page not captured |
| Opioid overdose | adult | 2 mg | IN | not captured | not captured | page not captured |
| Opioid overdose | adult | 2 mg | IM | not captured | not captured | page not captured |
| Opioid overdose | adult | 2 mg | IV | not captured | not captured | page not captured |
| Opioid overdose | peds | 0.1 mg/kg | IM | not captured | not captured | page not captured |
| Opioid overdose | peds | 0.1 mg/kg | IV | not captured | not captured | page not captured |
| Opioid overdose | peds | 0.5 mg | IN | not captured | not captured | page not captured |
| Opioid overdose | peds | 1 mg | IN | not captured | not captured | page not captured |
| Opioid overdose | peds | 1.5 mg | IN | not captured | not captured | page not captured |
Nitroglycerin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| ACS / chest pain | adult | 0.4 mg | SL | not captured | not captured | page not captured |
| CHF / pulmonary edema | adult | 0.4 mg | SL | not captured | not captured | page not captured |
Ondansetron
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Nausea / vomiting | adult | 0.1 mg/kg | IV/IM | not captured | not captured | page not captured |
| Nausea / vomiting | adult | 4 mg | ODT | not captured | not captured | page not captured |
| Nausea / vomiting | adult | 4 mg | IV/IM | not captured | not captured | page not captured |
| Nausea / vomiting | peds | 0.1 mg/kg | IV/IM | not captured | not captured | page not captured |
Pralidoxime
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Nerve agent exposure | adult | 600 mg | IV/IM | not captured | not captured | page not captured |
Prednisone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Adrenal crisis | adult | 50 mg | PO | not captured | not captured | page not captured |
| Allergic reaction | adult | 50 mg | PO | not captured | not captured | page not captured |
| Respiratory distress | adult | 50 mg | PO | not captured | not captured | page not captured |
Racemic Epinephrine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Stridor | adult | 0.5 mL | NEB | not captured | not captured | page not captured |
| Stridor | peds | 0.5 mL | NEB | not captured | not captured | page not captured |
Sodium Bicarbonate
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 1 mEq/kg | IV/IO | not captured | not captured | page not captured |
| Other | adult | 1 mEq/kg | IV/IO | not captured | not captured | page not captured |
| Other | peds | 1 mEq/kg | IV/IO | not captured | not captured | page not captured |
| Tricyclic overdose | adult | 1 mEq/kg | IV | not captured | not captured | page not captured |
| Tricyclic overdose | adult | 50 mEq | IV | not captured | not captured | page not captured |
| Tricyclic overdose | peds | 1 mEq/kg | IV | not captured | not captured | page not captured |
Tetracaine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Mild to moderate pain | adult | 1–2 drop | not captured | not captured | not captured | page not captured |
Tranexamic Acid
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Trauma / hemorrhage | adult | 1 g | IV/IO | not captured | not captured | page not captured |
Verapamil
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Narrow-complex tachycardia | adult | 5 mg | IV | not captured | not captured | page not captured |