Statewide
Ministry of Health, Emergency Health Regulatory and Accountability Branch
Ministry of Health, Emergency Health Regulatory and Accountability Branch (ON) carries 32 drugs across 90 dose entries in its current published protocol, effective 2025-06-02.
Drugs and doses32
Acetaminophen
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 960–1000 mg | PO | not captured | standing | pages 217, 264 |
| Other | adult | 960–1000 mg | PO | not captured | standing | pages 219, 266 |
| Mild to moderate pain | adult | 960–1000 mg | PO | not captured | standing | pages 81, 176 |
| Mild to moderate pain | peds | 500–650 mg | PO | not captured | standing | pages 81, 176 |
Adenosine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 6 mg | IV | not captured | standing | page 147 |
Amiodarone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 300 mg | IV/IO | not captured | standing | page 117 |
| Other | peds | 5 mg/kg | IV/IO | not captured | standing | page 117 |
Atropine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Bradycardia | adult | 1 mg | IV | not captured | standing | page 143 |
| Nerve agent exposure | adult | 2 mg | IM | not captured | standing | pages 234, 281 |
| Nerve agent exposure | peds | 0.5 mg | IM | not captured | standing | pages 234, 281 |
Buprenorphine-Naloxone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Opioid overdose | adult | 16 mg | SL | not captured | standing | pages 74, 168 |
Calcium Gluconate
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hyperkalemia | adult | 1 g | IV/IO | not captured | standing | page 151 |
Dexamethasone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Croup | adult | 0.5 mg/kg | PO | not captured | standing | pages 43, 105 |
| Croup | peds | 0.5 mg/kg | PO | not captured | standing | pages 43, 105 |
| Other | adult | 0.5 mg/kg | IV/IM/PO | not captured | standing | pages 38, 100 |
| Other | peds | 0.5 mg/kg | IV/IM/PO | not captured | standing | pages 38, 100 |
Dextrose
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hypoglycemia | adult | 0.5 g/kg | IV | not captured | standing | pages 69, 160 |
| Hypoglycemia | peds | 0.2 g/kg | IV | not captured | standing | pages 69, 160 |
Diazepam
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Nerve agent exposure | adult | 10 mg | IM | not captured | standing | pages 230, 235, 277, 282 |
| Nerve agent exposure | peds | 0.2 mg/kg | IM | not captured | standing | pages 230, 235, 277, 282 |
Dimenhydrinate
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Nausea / vomiting | adult | 50 mg | IV/IM | not captured | standing | pages 84, 183 |
| Nausea / vomiting | peds | 25 mg | IV/IM | not captured | standing | pages 84, 183 |
Diphenhydramine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 50 mg | IV/IM | not captured | standing | pages 41, 103 |
| Other | adult | 50 mg | PO | not captured | standing | pages 215, 262 |
| Other | peds | 25 mg | IV/IM | not captured | standing | pages 41, 103 |
Dopamine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Bradycardia | adult | 5 mcg/kg | IV | not captured | standing | page 143 |
| Cardiogenic shock | adult | 5 mcg/kg | IV | not captured | standing | page 140 |
| Post-ROSC care | adult | 5 mcg/kg | IV | not captured | standing | page 131 |
Epinephrine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Cardiac arrest | adult | 0.01 mg/kg | IM | not captured | standing | pages 51, 116 |
| Cardiac arrest | adult | 1 mg | IV/IO | not captured | standing | page 116 |
| Cardiac arrest | adult | 2 mg | ET | not captured | standing | page 116 |
| Cardiac arrest | peds | 0.01 mg/kg | IM | not captured | standing | pages 51, 116 |
| Cardiac arrest | peds | 0.01 mg/kg | IV/IO | not captured | standing | page 116 |
| Neonatal resuscitation | peds | 0.01 mg/kg | IV/IO | not captured | standing | page 126 |
| Other | peds | 0.01 mg/kg | IM | not captured | standing | pages 38, 100 |
| Other | peds | 0.01 mg/kg | IM | not captured | standing | pages 41, 103 |
Fentanyl
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Mild to moderate pain | adult | 25–75 mcg | IV/IN | not captured | standing | page 177 |
| Mild to moderate pain | peds | 1 mcg/kg | IV/IN | not captured | standing | page 177 |
| Procedural sedation | adult | 25–75 mcg | IV/IO/IN | not captured | standing | page 252 |
Glucagon
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hypoglycemia | adult | 1 mg | IM | not captured | standing | pages 70, 161 |
| Hypoglycemia | adult | 3 mg | IN | not captured | standing | pages 70, 161 |
| Hypoglycemia | peds | 0.5 mg | IM | not captured | standing | pages 70, 161 |
Hydrocortisone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 2 mg/kg | IV/IM/PO | not captured | standing | pages 38, 78, 100, 172 |
| Other | peds | 2 mg/kg | IV/IM/PO | not captured | standing | pages 38, 78, 100, 172 |
Hydroxocobalamin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Cyanide poisoning | adult | 5 g | IV | not captured | standing | pages 222, 269 |
| Cyanide poisoning | peds | 70 mg/kg | IV | not captured | standing | pages 222, 269 |
Ibuprofen
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Mild to moderate pain | adult | 400 mg | PO | not captured | standing | pages 82, 176 |
Ketamine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Agitation | adult | 5 mg/kg | IM | not captured | standing | page 180 |
| Mild to moderate pain | adult | 0.25 mg/kg | IV | not captured | standing | page 178 |
| Mild to moderate pain | peds | 0.25 mg/kg | IV | not captured | standing | page 178 |
Ketorolac
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Mild to moderate pain | adult | 10–15 mg | IV/IM | not captured | standing | pages 82, 176 |
Lidocaine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 1.5 mg/kg | IV/IO | not captured | standing | page 117 |
| Other | adult | 3 mg/kg | ET | not captured | standing | page 117 |
| Other | peds | 1 mg/kg | IV/IO | not captured | standing | page 117 |
Midazolam
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Agitation | adult | 0.1 mg/kg | IV/IM/IN | not captured | standing | page 180 |
| Nerve agent exposure | adult | 10 mg | IM | not captured | standing | pages 230, 235, 277, 282 |
| Nerve agent exposure | peds | 0.2 mg/kg | IM | not captured | standing | pages 230, 235, 277, 282 |
| Procedural sedation | adult | 0.1 mg/kg | IV/IO/IN | not captured | standing | page 252 |
| Seizure | adult | 0.1 mg/kg | IV/IO | not captured | standing | page 165 |
| Seizure | adult | 0.2 mg/kg | IM/IN | not captured | standing | page 165 |
| Seizure | peds | 0.1 mg/kg | IV/IO | not captured | standing | page 165 |
| Seizure | peds | 0.2 mg/kg | IM/IN | not captured | standing | page 165 |
Morphine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 2 mg | IV | not captured | standing | page 135 |
| Mild to moderate pain | adult | 2–10 mg | IV/SQ | not captured | standing | page 177 |
| Mild to moderate pain | peds | 0.05–0.1 mg/kg | IV/SQ | not captured | standing | page 177 |
Naloxone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Opioid overdose | adult | 0.4 mg | IM | not captured | standing | pages 74, 168 |
| Opioid overdose | adult | 0.8 mg | SQ | not captured | standing | pages 74, 168 |
| Opioid overdose | adult | 2–4 mg | IN | not captured | standing | pages 74, 168 |
| Opioid overdose | adult | 0.4 mg | IV/IO | not captured | standing | pages 74, 168 |
| Opioid overdose | peds | 0.4 mg | IM | not captured | standing | pages 74, 168 |
| Opioid overdose | peds | 0.8 mg | SQ | not captured | standing | pages 74, 168 |
| Opioid overdose | peds | 2–4 mg | IN | not captured | standing | pages 74, 168 |
| Opioid overdose | peds | 0.4 mg | IV/IO | not captured | standing | pages 74, 168 |
Nitroglycerin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| CHF / pulmonary edema | adult | 0.3 mg | SL | not captured | standing | pages 67, 137 |
| Other | adult | 0.3 mg | SL | not captured | standing | pages 65, 135 |
Ondansetron
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Nausea / vomiting | adult | 4 mg | IV/IM/PO | not captured | standing | pages 84, 183 |
Oxytocin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 10 unit | IM | not captured | standing | pages 90, 189 |
Pralidoxime
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Nerve agent exposure | adult | 600 mg | IM | not captured | standing | pages 229, 234, 276, 281 |
| Nerve agent exposure | peds | 15 mg/kg | IM | not captured | standing | pages 229, 234, 276, 281 |
Salbutamol
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hyperkalemia | adult | 1600 mcg | MDI | not captured | standing | page 152 |
| Hyperkalemia | adult | 10 mg | NEB | not captured | standing | page 152 |
| Other | adult | 5 mg | NEB | not captured | standing | pages 38, 100 |
| Other | adult | 800 mcg | MDI | not captured | standing | pages 38, 100 |
| Other | peds | 2.5 mg | NEB | not captured | standing | pages 38, 100 |
| Other | peds | 600 mcg | MDI | not captured | standing | pages 38, 100 |
Sodium Thiosulfate
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Cyanide poisoning | adult | 12.5 g | IV | not captured | standing | pages 221, 268 |
| Cyanide poisoning | peds | 400 mg/kg | IV | not captured | standing | pages 221, 268 |
Tranexamic Acid
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Trauma / hemorrhage | adult | 1000 mg | IV | not captured | standing | pages 197, 248 |
| Trauma / hemorrhage | adult | 1000 mg | IM | not captured | standing | pages 197, 248 |
Xylometazoline
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| RSI induction | adult | 2 spray | TOP | not captured | standing | page 241 |