Statewide
North Carolina Office of Emergency Medical Services (NC OEMS)
North Carolina Office of Emergency Medical Services (NC OEMS) (NC) carries 42 drugs across 136 dose entries in its current published protocol, effective 2025-09-01.
Drugs and doses42
Acetaminophen
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Fever | adult | 325–1000 mg | PO | not captured | standing | page 20 |
| Fever | peds | 15 mg/kg | PO | not captured | standing | page 20 |
| Mild to moderate pain | adult | 1 g | IV | not captured | standing | page 21 |
| Mild to moderate pain | adult | 325–1000 mg | PO | not captured | standing | page 21 |
| Mild to moderate pain | peds | 15 mg/kg | PO | not captured | standing | page 21 |
| Mild to moderate pain | peds | 15 mg/kg | IV | not captured | standing | page 21 |
Activated Charcoal
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 50 g | PO | not captured | standing | page 163 |
| Other | peds | 1 g/kg | PO | not captured | standing | page 163 |
Adenosine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Narrow-complex tachycardia | adult | 6 mg | IV/IO | not captured | standing | page 72 |
| Narrow-complex tachycardia | peds | 0.1 mg/kg | IV/IO | not captured | standing | page 72 |
Albuterol
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Asthma / bronchospasm | adult | 2.5–5 mg | NEB | not captured | standing | page 47 |
| Asthma / bronchospasm | peds | 1.25–2.5 mg | NEB | not captured | standing | page 47 |
| Respiratory distress | adult | 2.5–5 mg | NEB | not captured | standing | page 47 |
| Respiratory distress | peds | 1.25–2.5 mg | NEB | not captured | standing | page 47 |
| Stridor | adult | 2.5–5 mg | NEB | not captured | standing | page 47 |
| Stridor | peds | 1.25–2.5 mg | NEB | not captured | standing | page 47 |
Amiodarone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Narrow-complex tachycardia | adult | 150 mg | IV/IO | not captured | standing | page 72 |
| VF / pulseless VT | adult | 300 mg | IV/IO | not captured | standing | page 78 |
| VF / pulseless VT | adult | 300 mg | IV/IO | not captured | standing | page 78 |
Aspirin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| ACS / chest pain | adult | 324 mg | PO | not captured | standing | page 68 |
| Mild to moderate pain | adult | 324–650 mg | PO | not captured | standing | page 21 |
Atropine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Bradycardia | adult | 1 mg | IV/IO | not captured | standing | page 64 |
| Bradycardia | peds | 0.02 mg/kg | IV/IO | not captured | standing | page 64 |
| Nerve agent exposure | adult | 2 mg | IV/IO/IM | not captured | standing | page 165 |
Calcium Chloride
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Crush injury | adult | 1 g | IV/IO | not captured | standing | page 116 |
| Hyperkalemia | adult | 1 g | IV/IO | not captured | standing | page 116 |
Calcium Gluconate
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Crush injury | adult | 2 g | IV/IO | not captured | standing | page 116 |
| Crush injury | peds | 20 mg/kg | IV/IO | not captured | standing | page 116 |
| Hyperkalemia | adult | 2 g | IV/IO | not captured | standing | page 116 |
| Hyperkalemia | peds | 20 mg/kg | IV/IO | not captured | standing | page 116 |
Dextrose
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hypoglycemia | adult | 125 mL | IV/IO | not captured | standing | page 114 |
| Hypoglycemia | peds | 5 mL/kg | IV/IO | not captured | standing | page 114 |
Diltiazem
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Narrow-complex tachycardia | adult | 0.25 mg/kg | IV/IO | not captured | standing | page 72 |
Diphenhydramine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Allergic reaction | adult | 25–50 mg | PO | not captured | standing | page 112 |
| Allergic reaction | adult | 25–50 mg | IV/IO/IM | not captured | standing | page 112 |
| Allergic reaction | peds | 1 mg/kg | PO | not captured | standing | page 112 |
| Allergic reaction | peds | 1 mg/kg | IV/IO/IM | not captured | standing | page 112 |
| Dystonic reaction | adult | 50 mg | IV/IO/IM/PO | not captured | standing | page 34 |
| Dystonic reaction | peds | 1 mg/kg | IV/IO/IM/PO | not captured | standing | page 34 |
Dopamine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Bradycardia | adult | 2–20 mcg/kg | IV/IO | not captured | standing | page 64 |
Epinephrine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Anaphylaxis | adult | 0.3–0.5 mg | IM | not captured | standing | page 112 |
| Anaphylaxis | peds | 0.01 mg/kg | IM | not captured | standing | page 112 |
| Bradycardia | adult | 1–10 mcg | IV/IO | not captured | standing | page 64 |
| Bradycardia | peds | 0.01 mg/kg | IV/IO | not captured | standing | page 64 |
| Cardiac arrest | adult | 1 mg | IV/IO | not captured | standing | page 62 |
| Cardiac arrest | peds | 0.01 mg/kg | IV/IO | not captured | standing | page 62 |
| Respiratory distress | adult | 0.3–0.5 mg | IM | not captured | standing | page 47 |
| Respiratory distress | peds | 0.01 mg/kg | IM | not captured | standing | page 47 |
| Stridor | adult | 1 mg | NEB | not captured | standing | page 47 |
| Stridor | peds | 1 mg | NEB | not captured | standing | page 47 |
Etomidate
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| RSI induction | adult | 0.3 mg/kg | IV/IO | not captured | standing | page 45 |
Fentanyl
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Mild to moderate pain | adult | 50–100 mcg | IV/IO/IM | not captured | standing | page 21 |
| Mild to moderate pain | peds | 1 mcg/kg | IV/IO/IM | not captured | standing | page 21 |
| Mild to moderate pain | peds | 1 mcg/kg | IN | not captured | standing | page 21 |
Furosemide
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| CHF / pulmonary edema | adult | 40 mg | IV | not captured | standing | page 70 |
| CHF / pulmonary edema | peds | 1 mg/kg | IV | not captured | standing | page 70 |
Glucagon
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hypoglycemia | adult | 1–2 mg | IM | not captured | standing | page 114 |
| Hypoglycemia | peds | 0.1 mg/kg | IM | not captured | standing | page 114 |
Haloperidol
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Agitation | adult | 2–5 mg | IM | not captured | standing | page 36 |
Hydroxocobalamin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Cyanide poisoning | adult | 70 mg/kg | IV/IO | not captured | standing | page 154 |
Ibuprofen
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Fever | adult | 400–600 mg | PO | not captured | standing | page 20 |
| Fever | peds | 10 mg/kg | PO | not captured | standing | page 20 |
| Mild to moderate pain | adult | 400–600 mg | PO | not captured | standing | page 21 |
| Mild to moderate pain | peds | 10 mg/kg | PO | not captured | standing | page 21 |
Ipratropium
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Respiratory distress | adult | 0.5 mg | NEB | not captured | standing | page 47 |
| Respiratory distress | peds | 0.5 mg | NEB | not captured | standing | page 47 |
Ketamine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hyperactive delirium | adult | 4 mg/kg | IM | not captured | standing | page 37 |
| Hyperactive delirium | peds | 2 mg/kg | IM | not captured | standing | page 37 |
| Mild to moderate pain | adult | 0.3 mg/kg | IV/IO | not captured | standing | page 21 |
| Post-intubation sedation | adult | 1.5–2 mg/kg | IV/IO | not captured | standing | page 55 |
| RSI induction | adult | 1–2 mg/kg | IV/IO | not captured | standing | page 45 |
| RSI induction | adult | 4 mg/kg | IM | not captured | standing | page 45 |
| RSI induction | peds | 2 mg/kg | IM | not captured | standing | page 45 |
Ketorolac
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Mild to moderate pain | adult | 15 mg | IV/IO | not captured | standing | page 21 |
| Mild to moderate pain | adult | 30 mg | IM | not captured | standing | page 21 |
| Mild to moderate pain | peds | 0.5 mg/kg | IV/IO | not captured | standing | page 21 |
| Mild to moderate pain | peds | 0.5 mg/kg | IM | not captured | standing | page 21 |
Lidocaine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| VF / pulseless VT | adult | 1–1.5 mg/kg | IV/IO | not captured | standing | page 78 |
| VF / pulseless VT | adult | 1–1.5 mg/kg | IV/IO | not captured | standing | page 78 |
Magnesium Sulfate
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Crush injury | adult | 2 g | IV/IO | not captured | standing | page 138 |
| Crush injury | peds | 20 mg/kg | IV/IO | not captured | standing | page 138 |
| Respiratory distress | adult | 2 g | IV/IO | not captured | standing | page 47 |
| Respiratory distress | peds | 40 mg/kg | IV/IO | not captured | standing | page 47 |
Methylprednisolone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Allergic reaction | adult | 125 mg | IV/IO | not captured | standing | page 112 |
| Allergic reaction | peds | 2 mg/kg | IV/IO | not captured | standing | page 112 |
| CHF / pulmonary edema | peds | 2 mg/kg | IV/IO | not captured | standing | page 101 |
| Respiratory distress | adult | 125 mg | IV/IO/IM | not captured | standing | page 47 |
| Respiratory distress | peds | 2 mg/kg | IV/IO/IM | not captured | standing | page 47 |
Midazolam
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Agitation | adult | 2.5 mg | IV/IO/IN | not captured | standing | page 36 |
| Agitation | adult | 5 mg | IM | not captured | standing | page 36 |
| Agitation | peds | 0.1–0.2 mg/kg | IV/IO/IN | not captured | standing | page 36 |
| Eclampsia / pre-eclampsia | adult | 10 mg | IM | not captured | standing | page 171 |
| Eclampsia / pre-eclampsia | adult | 2–2.5 mg | IV/IO | not captured | standing | page 171 |
| Eclampsia / pre-eclampsia | peds | 0.2 mg | IV/IO | not captured | standing | page 171 |
| Eclampsia / pre-eclampsia | peds | 0.2 mg/kg | IM | not captured | standing | page 171 |
| Hyperactive delirium | adult | 10 mg | IM | not captured | standing | page 37 |
| Hyperactive delirium | peds | 0.1–0.2 mg/kg | IM | not captured | standing | page 37 |
| Post-intubation sedation | adult | 2–2.5 mg | IV/IO | not captured | standing | page 55 |
| Post-intubation sedation | peds | 0.1–0.2 mg/kg | IV/IO | not captured | standing | page 55 |
| Procedural sedation | adult | 2–2.5 mg | IV/IO | not captured | standing | page 72 |
| Procedural sedation | peds | 0.1–0.2 mg/kg | IV/IO | not captured | standing | page 72 |
| Seizure | adult | 10 mg | IM | not captured | standing | page 25 |
| Seizure | adult | 2–2.5 mg | IV/IO | not captured | standing | page 25 |
| Seizure | peds | 0.2 mg/kg | IV/IO | not captured | standing | page 25 |
| Seizure | peds | 0.2 mg/kg | IM | not captured | standing | page 25 |
Morphine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| CHF / pulmonary edema | peds | 0.1 mg/kg | IV/IO | not captured | standing | page 101 |
| Mild to moderate pain | adult | 4 mg | IV/IO/IM | not captured | standing | page 21 |
| Mild to moderate pain | peds | 0.1 mg/kg | IV/IO/IM | not captured | standing | page 21 |
Naloxone
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Opioid overdose | adult | 0.4–2 mg | IM/IN | not captured | standing | page 66 |
| Opioid overdose | adult | 0.4–2 mg | IV/IO/IM/IN/ET | not captured | standing | page 66 |
| Opioid overdose | peds | 0.1 mg/kg | IM/IN | not captured | standing | page 66 |
| Opioid overdose | peds | 0.1 mg/kg | IV/IO/IM/IN/ET | not captured | standing | page 66 |
Nitrous Oxide
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Mild to moderate pain | adult | 70:30 to 50:50 Mix NO/O2 | NEB | not captured | standing | page 21 |
Ondansetron
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Nausea / vomiting | adult | 4 mg | IV/IO/IM/PO/ODT | not captured | standing | page 7 |
| Nausea / vomiting | peds | 0.2 mg/kg | IV/IO/IM/PO/ODT | not captured | standing | page 7 |
Oral Glucose
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Hypoglycemia | adult | 1/2 to 1 Tube | PO | not captured | standing | page 127 |
| Hypoglycemia | peds | 1/2 to 1 Tube | PO | not captured | standing | page 127 |
Oxymetazoline
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 2 spray | IN | not captured | standing | page 18 |
Oxytocin
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Obstetric hemorrhage | adult | 10 unit | IM | not captured | standing | page 167 |
Pralidoxime
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Nerve agent exposure | adult | 600 mg | IV/IO/IM | not captured | standing | page 165 |
| Nerve agent exposure | peds | 15–25 mg/kg | IV/IO/IM | not captured | standing | page 165 |
Promethazine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Nausea / vomiting | adult | 12.5 mg | IM/PO | not captured | standing | page 7 |
Rocuronium
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Post-intubation sedation | adult | 0.6–1.2 mg/kg | IV/IO | not captured | standing | page 55 |
| RSI induction | adult | 1 mg/kg | IV/IO | not captured | standing | page 45 |
Sodium Bicarbonate
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Crush injury | adult | 50 mEq | IV/IO | not captured | standing | page 116 |
| Crush injury | peds | 1 mEq/kg | IV/IO | not captured | standing | page 116 |
| Hyperkalemia | adult | 50 mEq | IV/IO | not captured | standing | page 116 |
| Hyperkalemia | peds | 1 mEq/kg | IV/IO | not captured | standing | page 116 |
Succinylcholine
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| RSI induction | adult | 2 mg/kg | IV/IO | not captured | standing | page 45 |
Tranexamic Acid
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Obstetric hemorrhage | adult | 2 g | IV/IO | not captured | standing | page 171 |
| Obstetric hemorrhage | peds | 20 mg/kg | IV/IO | not captured | standing | page 171 |
| Other | adult | 1 g | TOP | not captured | standing | page 18 |
| Trauma / hemorrhage | adult | 1–2 g | IV/IO | not captured | standing | page 143 |
| Trauma / hemorrhage | adult | 1 g | TOP | not captured | standing | page 15 |
Vecuronium
| Indication | Population | Dose | Route | Repeat | Standing | Source |
|---|---|---|---|---|---|---|
| Other | adult | 10 mg | IV/IO | not captured | standing | page 86 |
| Post-intubation sedation | adult | 10 mg | IV/IO | not captured | standing | page 55 |