Protocol census · a finding

Same call, different dose

Lowest to highest adult dose across agencies. Box is the middle half; line is the median; a dot means most agree on one dose.

Every well-covered call adult, fixed doses, 15+ protocols each

Call	Dose range	Agencies
ACS / chest painAspirin	Most use 324 mg of 160 to 325 mg	131
ACS / chest painFentanyl	25 to 100 mcg	15
ACS / chest painMorphine	Most use 2 mg of 2 to 4 mg	21
ACS / chest painNitroglycerin	Most use 1 in of 0.5 to 1 in	12
ACS / chest painNitroglycerin	Most use 0.4 mg of 0.3 to 0.4 mg	138
Adrenal crisisDexamethasone	Most use 10 mg of 4 to 16 mg	15
Adrenal crisisHydrocortisone	Most use 100 mg of 75 to 100 mg	21
Adrenal crisisMethylprednisolone	Most use 125 mg of 60 to 125 mg	33
AgitationDiazepam	1 to 5 mg	28
AgitationDroperidol	2 to 10 mg	32
AgitationHaloperidol	2 to 10 mg	39
AgitationLorazepam	0.5 to 2.6 mg	44
AgitationMidazolam	2 to 10 mg	90
AgitationOlanzapine	5 to 10 mg	18
Allergic reactionAlbuterol	2.5 to 5 mg	20
Allergic reactionDexamethasone	Most use 10 mg of 4 to 16 mg	12
Allergic reactionDiphenhydramine	12.5 to 50 mg	105
Allergic reactionEpinephrine	Most use 0.3 mg of 0.2 to 0.5 mg	26
Allergic reactionMethylprednisolone	All use 125 mg	39
AnaphylaxisAlbuterol	Most use 2.5 mg of 2.5 to 5 mg	23
AnaphylaxisDexamethasone	Most use 10 mg of 4 to 20 mg	18
AnaphylaxisDiphenhydramine	25 to 50 mg	49
AnaphylaxisEpinephrine	Most use 0.3 mg of 0.1 to 0.5 mg	130
AnaphylaxisIpratropium	All use 0.5 mg	13
AnaphylaxisMethylprednisolone	Most use 125 mg of 62.5 to 125 mg	49
Asthma / bronchospasmAlbuterol	Most use 2.5 mg of 2.5 to 5 mg	112
Asthma / bronchospasmDexamethasone	Most use 10 mg of 4 to 16 mg	22
Asthma / bronchospasmEpinephrine	Most use 0.3 mg of 0.1 to 0.5 mg	69
Asthma / bronchospasmIpratropium	Most use 0.5 mg of 0.25 to 0.5 mg	92
Asthma / bronchospasmMagnesium sulfate	Most use 2 g of 1 to 2.5 g	91
Asthma / bronchospasmMethylprednisolone	All use 125 mg	65
Atrial fibrillation with RVRDiltiazem	7.5 to 25 mg	20
Beta-blocker / calcium-channel-blocker overdoseCalcium chloride	Most use 1000 mg of 500 to 1000 mg	67
Beta-blocker / calcium-channel-blocker overdoseCalcium gluconate	1 to 3 g	33
Beta-blocker / calcium-channel-blocker overdoseGlucagon	1 to 5 mg	83
BradycardiaAtropine	0.5 to 1 mg	144
BradycardiaEpinephrine	Most use 2 mcg of 1 to 6 mcg	57
Cardiac arrestAmiodarone	Most use 300 mg of 225 to 300 mg	42
Cardiac arrestCalcium chloride	Most use 1000 mg of 500 to 1000 mg	23
Cardiac arrestEpinephrine	Most use 1 mg of 0.5 to 2 mg	142
Cardiac arrestSodium bicarbonate	Most use 50 mEq of 50 to 100 mEq	17
CHF / pulmonary edemaFurosemide	Most use 40 mg of 20 to 80 mg	33
CHF / pulmonary edemaNitroglycerin	Most use 1 in of 0.5 to 2 in	15
CHF / pulmonary edemaNitroglycerin	Most use 0.4 mg of 0.3 to 1.2 mg	125
COPDAlbuterol	2.5 to 5 mg	17
COPDIpratropium	All use 0.5 mg	15
COPDMethylprednisolone	All use 125 mg	26
Crush injuryAlbuterol	2.5 to 15 mg	21
Crush injuryCalcium chloride	Most use 1000 mg of 500 to 1000 mg	23
Crush injurySodium bicarbonate	50 to 100 mEq	33
Cyanide poisoningHydroxocobalamin	All use 5 g	86
Cyanide poisoningSodium thiosulfate	All use 12.5 g	15
Dystonic reactionDiphenhydramine	25 to 50 mg	90
Eclampsia / pre-eclampsiaLabetalol	10 to 20 mg	12
Eclampsia / pre-eclampsiaMagnesium sulfate	Most use 4 g of 2 to 10 g	96
Eclampsia / pre-eclampsiaMidazolam	2 to 7.5 mg	10
FeverAcetaminophen	325 to 1000 mg	53
FeverIbuprofen	200 to 800 mg	37
Hyperactive deliriumMidazolam	2.5 to 10 mg	29
HyperkalemiaAlbuterol	2.5 to 15 mg	64
HyperkalemiaCalcium chloride	Most use 1000 mg of 500 to 1000 mg	91
HyperkalemiaCalcium gluconate	1 to 3 g	46
HyperkalemiaSodium bicarbonate	Most use 50 mEq of 44 to 150 mEq	59
HypoglycemiaDextrose	10 to 50 g	98
HypoglycemiaDextrose	50 to 250 mL	34
HypoglycemiaGlucagon	Most use 1 mg of 0.5 to 2 mg	119
HypoglycemiaOral glucose	Most use 15 g of 10 to 30 g	79
Hypotension / shockEpinephrine	5 to 20 mcg	47
Hypotension / shockEpinephrine	Most use 1 mL of 0.5 to 1 mL	15
Hypotension / shockNorepinephrine	1 to 5 mcg	44
Mild to moderate painAcetaminophen	325 to 1000 mg	97
Mild to moderate painFentanyl	25 to 100 mcg	68
Mild to moderate painHydromorphone	0.2 to 1 mg	17
Mild to moderate painIbuprofen	200 to 800 mg	59
Mild to moderate painKetamine	10 to 40 mg	19
Mild to moderate painKetorolac	10 to 45 mg	82
Mild to moderate painLidocaine	20 to 100 mg	56
Mild to moderate painMorphine	1 to 5 mg	62
Mild to moderate painTetracaine	1 to 2 drops	25
Narrow-complex tachycardiaAdenosine	6 to 12 mg	45
Narrow-complex tachycardiaAmiodarone	All use 150 mg	28
Narrow-complex tachycardiaDiltiazem	7.5 to 20 mg	14
Narrow-complex tachycardiaMetoprolol	Most use 5 mg of 2.5 to 5 mg	19
Nausea / vomitingDiphenhydramine	12.5 to 50 mg	23
Nausea / vomitingDroperidol	0.5 to 2.5 mg	37
Nausea / vomitingMetoclopramide	5 to 10 mg	20
Nausea / vomitingOndansetron	Most use 4 mg of 4 to 8 mg	139
Nausea / vomitingPromethazine	6.25 to 25 mg	35
Nerve agent exposureAtropine	Most use 2 mg of 1 to 4 mg	50
Nerve agent exposureDiazepam	2.5 to 10 mg	15
Nerve agent exposurePralidoxime	600 to 1200 mg	44
Obstetric hemorrhageOxytocin	10 to 20 units	41
Obstetric hemorrhageTranexamic acid	750 to 2000 mg	42
Opioid overdoseNaloxone	0.4 to 2 mg	122
Organophosphate poisoningAtropine	Most use 2 mg of 1 to 4 mg	88
Organophosphate poisoningPralidoxime	600 to 1800 mg	24
Post-intubation sedationFentanyl	25 to 100 mcg	16
Post-intubation sedationMidazolam	2 to 5 mg	28
Procedural sedationDiazepam	2 to 5 mg	28
Procedural sedationFentanyl	25 to 100 mcg	22
Procedural sedationLorazepam	0.5 to 2 mg	25
Procedural sedationMidazolam	1 to 5 mg	94
Respiratory distressAlbuterol	Most use 2.5 mg of 1.88 to 5 mg	38
Respiratory distressEpinephrine	Most use 0.3 mg of 0.22 to 0.5 mg	27
Respiratory distressIpratropium	All use 0.5 mg	26
Respiratory distressMagnesium sulfate	Most use 2 g of 1 to 2 g	19
Respiratory distressMethylprednisolone	Most use 125 mg of 62.5 to 125 mg	22
RSI inductionMidazolam	1 to 5 mg	20
SeizureDiazepam	2 to 10 mg	53
SeizureLorazepam	1 to 4 mg	47
SeizureMagnesium sulfate	Most use 4 g of 2 to 5 g	21
SeizureMidazolam	2 to 10 mg	118
SepsisNorepinephrine	Most use 2 mcg of 1 to 4 mcg	17
Severe painFentanyl	25 to 75 mcg	11
Severe painKetorolac	10 to 45 mg	21
Severe painMorphine	2 to 6 mg	14
STEMIAspirin	Most use 324 mg of 234 to 325 mg	15
SVTAdenosine	6 to 12 mg	74
Trauma / hemorrhageCefazolin	Most use 2 g of 1 to 3 g	26
Trauma / hemorrhageTranexamic acid	500 to 2000 mg	115
Tricyclic overdoseSodium bicarbonate	Most use 50 mEq of 50 to 100 mEq	42
VF / pulseless VTAmiodarone	Most use 300 mg of 150 to 300 mg	76
VF / pulseless VTMagnesium sulfate	Most use 2 g of 1 to 4 g	93
Wide-complex tachycardiaAdenosine	Most use 6 mg of 6 to 12 mg	17
Wide-complex tachycardiaAmiodarone	Most use 150 mg of 150 to 300 mg	75
Wide-complex tachycardiaMagnesium sulfate	Most use 2 g of 1 to 2 g	29

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