Drug

Midazolam in US EMS protocols

1,335 under review180 sources158 named agencies42 statesas of 2026-09-20

180 published protocols carry Midazolam across 32 indications, from 158 named agencies in 42 states.

180protocols

158named agencies

42states

32indications

1,900dose entries

99% of 1,900machine-parsed

1,335 rows are under review across the census and excluded from every number on this page. How that works.

Indications32

ACS / chest pain n=8
Atrial fibrillation with RVR n=2
Agitation n=116
Alcohol withdrawal n=5
Asthma / bronchospasm n=1
Beta-blocker / calcium-channel-blocker overdose n=1
Bradycardia n=11
Cardiac arrest n=3
CHF / pulmonary edema n=4
COPD n=1
Dystonic reaction n=2
Eclampsia / pre-eclampsia n=16
Hyperactive delirium n=33
Head injury / TBI n=1
Hyperthermia n=6
Hypothermia n=1
Nausea / vomiting n=2
Nerve agent exposure n=14
Organophosphate poisoning n=2
Other n=98
Mild to moderate pain n=10
Post-intubation sedation n=35
Post-ROSC care n=5
Procedural sedation n=122
Respiratory distress n=1
RSI induction n=30
Seizure n=154
Status epilepticus n=8
SVT n=4
Narrow-complex tachycardia n=13
Wide-complex tachycardia n=9
VF / pulseless VT n=1

Published distributions32

Only groups with at least 5 sources publish a distribution; thinner groups show their count alone.

Indication	Population	Sources	Median	Middle half	Unit
ACS / chest pain	Adult	8	3.125	2.5–3.5938	mg
Agitation	Adult	101	3.75	2.5–5	mg
Agitation	Adult, weight-based	16	0.1	0.0938–0.1125	mg/kg
Agitation	Pediatric, weight-based	65	0.1	0.1–0.15	mg/kg
Bradycardia	Adult	11	2.5	2–2.5	mg
Eclampsia / pre-eclampsia	Adult	16	5	4.375–7.5	mg
Hyperactive delirium	Adult	30	7.5	5–10	mg
Hyperactive delirium	Pediatric, weight-based	16	0.1	0.1–0.1	mg/kg
Hyperthermia	Pediatric, weight-based	5	0.1	0.1–0.15	mg/kg
Nerve agent exposure	Adult	11	6	4.375–7.5	mg
Nerve agent exposure	Pediatric, weight-based	9	0.2	0.15–0.2	mg/kg
Other	Adult	80	2	2–3.75	mg
Other	Adult, weight-based	32	0.1	0.1–0.1	mg/kg
Other	Pediatric, weight-based	60	0.1	0.1–0.1	mg/kg
Mild to moderate pain	Adult	7	2	2–2.5	mg
Post-intubation sedation	Adult	31	2.5	2–2.5	mg
Post-intubation sedation	Adult, weight-based	5	0.1	0.05–0.1	mg/kg
Post-intubation sedation	Pediatric, weight-based	19	0.1	0.075–0.1	mg/kg
Procedural sedation	Adult	111	2	2–2.5	mg
Procedural sedation	Adult, weight-based	14	0.1	0.1–0.1	mg/kg
Procedural sedation	Pediatric, weight-based	69	0.1	0.05–0.1	mg/kg
RSI induction	Adult	22	2.5	2–5	mg
RSI induction	Adult, weight-based	9	0.1	0.1–0.15	mg/kg
RSI induction	Pediatric, weight-based	14	0.1	0.1–0.1875	mg/kg
Seizure	Adult	132	5	3.75–7.5	mg
Seizure	Adult, weight-based	30	0.15	0.1–0.1875	mg/kg
Seizure	Pediatric, weight-based	129	0.15	0.1–0.2	mg/kg
Status epilepticus	Adult	6	6.25	5–7.5	mg
Status epilepticus	Pediatric, weight-based	5	0.2	0.2–0.2	mg/kg
Narrow-complex tachycardia	Adult	10	2.5	2.125–2.5	mg
Narrow-complex tachycardia	Pediatric, weight-based	7	0.1	0.0625–0.2	mg/kg
Wide-complex tachycardia	Adult	9	2.5	2–2.5	mg

Named agencies

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.

7 more agencies are counted but have too little published detail for a page yet.

Cite this

United States EMS Protocol Census, Midazolam: n=180 protocols from 158 named agencies / 42 states, as of 2026-09-20

Each distribution on this page carries its own n. A per-indication figure is narrower than this drug-wide one, and the group's own citation line is the one to quote for it.