Drug

Epinephrine in US EMS protocols

1,335 under review184 sources162 named agencies42 statesas of 2026-09-20

184 published protocols carry Epinephrine across 28 indications, from 162 named agencies in 42 states.

184protocols

162named agencies

42states

28indications

1,491dose entries

97% of 1,491machine-parsed

1,335 rows are under review across the census and excluded from every number on this page. How that works.

Indications28

Allergic reaction n=26
Anaphylaxis n=155
Asthma / bronchospasm n=92
Asystole / PEA n=6
Beta-blocker / calcium-channel-blocker overdose n=1
Bradycardia n=122
Burns n=1
Carbon monoxide poisoning n=1
Cardiac arrest n=165
Cardiogenic shock n=6
CHF / pulmonary edema n=1
COPD n=2
Croup n=42
Cyanide poisoning n=2
Head injury / TBI n=1
Hypotension / shock n=76
Hypothermia n=1
Neonatal resuscitation n=13
Opioid overdose n=1
Other n=31
Post-ROSC care n=5
Respiratory distress n=43
RSI induction n=3
Sepsis n=15
Stridor n=21
Trauma / hemorrhage n=3
Traumatic arrest n=1
VF / pulseless VT n=2

Published distributions40

Only groups with at least 5 sources publish a distribution; thinner groups show their count alone.

Indication	Population	Sources	Median	Middle half	Unit
Allergic reaction	Adult	26	0.3	0.3–0.3	mg
Allergic reaction	Pediatric	7	0.15	0.15–0.15	mg
Allergic reaction	Pediatric, weight-based	14	0.01	0.01–0.01	mg/kg
Anaphylaxis	Adult	151	0.3	0.3–0.3	mg
Anaphylaxis	Adult	5	0.5	0.5–1	mL
Anaphylaxis	Adult, weight-based	5	0.01	0.01–0.01	mg/kg
Anaphylaxis	Pediatric	47	0.15	0.15–0.15	mg
Anaphylaxis	Pediatric, weight-based	89	0.01	0.01–0.01	mg/kg
Asthma / bronchospasm	Adult	80	0.3	0.3–0.3	mg
Asthma / bronchospasm	Adult, weight-based	5	0.01	0.01–0.01	mg/kg
Asthma / bronchospasm	Pediatric	13	0.15	0.15–0.15	mg
Asthma / bronchospasm	Pediatric, weight-based	55	0.01	0.01–0.01	mg/kg
Asystole / PEA	Adult	5	1	1–1	mg
Bradycardia	Adult	64	0.002	0.002–0.002	mg
Bradycardia	Adult	6	0.5	0.5–0.875	mL
Bradycardia	Pediatric, weight-based	80	0.01	0.01–0.01	mg/kg
Cardiac arrest	Adult	161	1	1–1	mg
Cardiac arrest	Adult, weight-based	9	0.01	0.01–0.01	mg/kg
Cardiac arrest	Pediatric, weight-based	133	0.01	0.01–0.01	mg/kg
Croup	Adult	5	1	1–3	mg
Croup	Pediatric	22	3	1.25–3	mg
Croup	Pediatric	9	3	2.5–5	mL
Croup	Pediatric, weight-based	5	0.5	0.5–0.5	mg/kg
Hypotension / shock	Adult	54	0.01	0.007–0.01	mg
Hypotension / shock	Adult	15	1	1–1	mL
Hypotension / shock	Adult, weight-based	6	0.0001	0.0001–0.0001	mg/kg
Hypotension / shock	Pediatric	6	0.01	0.0063–0.01	mg
Hypotension / shock	Pediatric, weight-based	18	0.001	0.001–0.001	mg/kg
Neonatal resuscitation	Pediatric, weight-based	11	0.01	0.01–0.01	mg/kg
Other	Adult	11	0.3	0.3–0.3	mg
Other	Pediatric	8	3	3–3.5	mg
Other	Pediatric, weight-based	13	0.01	0.01–0.01	mg/kg
Respiratory distress	Adult	30	0.3	0.3–0.3	mg
Respiratory distress	Pediatric	6	0.5	0.5–0.875	mg
Respiratory distress	Pediatric, weight-based	16	0.01	0.01–0.01	mg/kg
Sepsis	Adult	7	0.01	0.01–0.01	mg
Sepsis	Pediatric, weight-based	6	0.0001	0.0001–0.0001	mg/kg
Stridor	Adult	8	5	5–5	mL
Stridor	Pediatric	10	2.75	2.125–4.5	mg
Stridor	Pediatric	6	5	3.125–5	mL

Named agencies

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.

7 more agencies are counted but have too little published detail for a page yet.