Drug

Diphenhydramine in US EMS protocols

1,335 under review174 sources152 named agencies42 statesas of 2026-09-20

174 published protocols carry Diphenhydramine across 9 indications, from 152 named agencies in 42 states.

174protocols

152named agencies

42states

9indications

892dose entries

99% of 892machine-parsed

1,335 rows are under review across the census and excluded from every number on this page. How that works.

Indications9

Only groups with at least 5 sources publish a distribution; thinner groups show their count alone.

Indication	Population	Sources	Median	Middle half	Unit
Agitation	Adult	6	50	50–50	mg
Allergic reaction	Adult	115	37.5	25–50	mg
Allergic reaction	Adult, weight-based	14	1	1–1	mg/kg
Allergic reaction	Pediatric, weight-based	106	1	1–1	mg/kg
Anaphylaxis	Adult	57	50	25–50	mg
Anaphylaxis	Adult, weight-based	12	1	1–1	mg/kg
Anaphylaxis	Pediatric, weight-based	60	1	1–1	mg/kg
Dystonic reaction	Adult	98	50	25–50	mg
Dystonic reaction	Adult, weight-based	11	1	1–1	mg/kg
Dystonic reaction	Pediatric, weight-based	71	1	1–1	mg/kg
Nausea / vomiting	Adult	27	25	12.5–25	mg
Nausea / vomiting	Pediatric, weight-based	20	1	1–1	mg/kg
Other	Adult	50	25	25–50	mg
Other	Pediatric, weight-based	31	1	1–1	mg/kg

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.

5 more agencies are counted but have too little published detail for a page yet.