Diphenhydramine for Anaphylaxis
Pediatric weight-based dosing has a median of 1 mg/kg across 60 published protocols, with the middle half between 1 and 1.
1,335 rows are under review across the census and excluded from every number on this page. How that works.
Pediatric, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 0.5 | 1 | 1 | 1 | 1.5 |
Values in mg/kg. One value per source (that source's median), so a document listing a drug five times still gets one vote.
Routes
- IV/IO/IM 29%
- IV/IM 28%
- IM 12%
- IV 9%
- PO 8%
- IV/IO 7%
- IV/IM/PO 5%
- IO/IM 1%
- IV/IO/IM/PO 1%
United States EMS Protocol Census, n=60 protocols from 50 named agencies / 29 states, updated Sep 2026
Adultmg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 25 | 25 | 50 | 50 | 50 |
Values in mg. One value per source (that source's median), so a document listing a drug five times still gets one vote.
Routes
- IV/IO/IM 27%
- IV/IM 22%
- IM 14%
- PO 13%
- IV 12%
- IV/IO 6%
- IV/IM/PO 4%
- IO/IM 1%
- IV/IO/IM/PO 1%
United States EMS Protocol Census, n=57 protocols from 49 named agencies / 27 states, updated Sep 2026
Adult, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 1 | 1 | 1 | 1 | 1 |
Values in mg/kg. One value per source (that source's median), so a document listing a drug five times still gets one vote.
Routes
- IV/IO/IM 50%
- IV/IM 42%
- IV/IM/PO 8%
United States EMS Protocol Census, n=12 protocols from 10 named agencies / 9 states, updated Sep 2026
Pediatricmg
Below 5 sources, so no distribution is published for this group — only the counts above.
Routes
- IV/IO/IM 100%
United States EMS Protocol Census, n=1 protocols from 1 named agencies / 1 states, updated Sep 2026
Named agencies
Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.
- Ada County-City Emergency Services System
- Alameda County Emergency Medical Services
- Ascension Saint Joseph Hospital EMS System
- BC Emergency Health Services
- BEST EMS
- Boulder County EMS
- Boulder County Protocol Committee
- Brigham City, Cache County, Logan City, Smithfield Fire Departments
- Brilliant Fire Department
- Cabarrus County EMS
- Campbell County Emergency Medical Service
- Central California Emergency Medical Services
- Cochran County Emergency Medical Services
- Confederated Tribes of Grand Ronde Department of Emergency Services
- County of Marin EMS
- County of Riverside Emergency Medical Services Agency
- County of Riverside Emergency Medical Services (EMS) Agency (REMSA)
- Delaware Office of Emergency Medical Services
- Fern Creek Fire and Emergency Medical Services
- FirstHealth of the Carolinas
- Franklin County Emergency Medical Services
- Giles County EMS
- Greater Miami Valley EMS Council
- Kern County Public Health
- Kershaw County Emergency Medical Services
- Laurens County Emergency Medical Services
- Marin County Emergency Medical Services Agency
- Maryland Institute for Emergency Medical Services Systems
- Metro Regional EMS Consortium
- Michigan Department of Health and Human Services (MDHHS) / Midland Gladwin MCA
- Michigan Department of Health and Human Services (MDHHS) / West Michigan Regional MCC
- Michigan Department of Health & Human Services, Bureau of Emergency Preparedness, EMS and Systems of Care
- Miramar Fire Rescue Department
- Montana Board of Medical Examiners
- Muskogee County EMS
- Nash County Emergency Medical Services
- National Emergency Medical Services
- New Hampshire Bureau of Emergency Medical Services
- New Jersey Department of Health
- New York State Department of Health, Bureau of Emergency Medical Services and Trauma Systems
- Northwest Community EMS System
- Ocala/Marion County Fire Rescue
- Office of the EMS Medical Director for Kansas City, Missouri
- Old Dominion EMS Alliance, Inc.
- Pend Oreille County Emergency Medical Services
- Pettis County Ambulance District
- Pierce County Emergency Medical Services
- Regional Emergency Medical Advisory Committee of New York City
- Riverside County Emergency Medical Services Agency (REMSA)
- Riverside County EMS Agency
- Southern Fox Valley EMS System
- Spokane County EMS
- Stanislaus County Emergency Medical Services Agency
- Stevens County Emergency Medical Services
- Tennessee Emergency Medical Services
- Tri County Emergency Medical Services, Inc.
- Utah Department of Public Safety, Bureau of Emergency Medical Services
- Wilson County Emergency Management Agency