US EMS Protocol Census
Indication

Diphenhydramine for Anaphylaxis

1,335 under review69 sources59 named agencies31 statesas of 2026-09-20

Pediatric weight-based dosing has a median of 1 mg/kg across 60 published protocols, with the middle half between 1 and 1.

69sources
59named agencies
31states
167entries
58named here

1,335 rows are under review across the census and excluded from every number on this page. How that works.

Pediatric, weight-basedmg/kg

60sources
50named agencies
29states
76entries
0kept as written
minp25medianp75max
0.51111.5

Values in mg/kg. One value per source (that source's median), so a document listing a drug five times still gets one vote.

Routes

  • IV/IO/IM 29%
  • IV/IM 28%
  • IM 12%
  • IV 9%
  • PO 8%
  • IV/IO 7%
  • IV/IM/PO 5%
  • IO/IM 1%
  • IV/IO/IM/PO 1%

United States EMS Protocol Census, n=60 protocols from 50 named agencies / 29 states, updated Sep 2026

Adultmg

57sources
49named agencies
27states
78entries
1kept as written
minp25medianp75max
2525505050

Values in mg. One value per source (that source's median), so a document listing a drug five times still gets one vote.

Routes

  • IV/IO/IM 27%
  • IV/IM 22%
  • IM 14%
  • PO 13%
  • IV 12%
  • IV/IO 6%
  • IV/IM/PO 4%
  • IO/IM 1%
  • IV/IO/IM/PO 1%

United States EMS Protocol Census, n=57 protocols from 49 named agencies / 27 states, updated Sep 2026

Adult, weight-basedmg/kg

12sources
10named agencies
9states
12entries
0kept as written
minp25medianp75max
11111

Values in mg/kg. One value per source (that source's median), so a document listing a drug five times still gets one vote.

Routes

  • IV/IO/IM 50%
  • IV/IM 42%
  • IV/IM/PO 8%

United States EMS Protocol Census, n=12 protocols from 10 named agencies / 9 states, updated Sep 2026

Pediatricmg

1sources
1named agencies
1states
1entries
0kept as written

Below 5 sources, so no distribution is published for this group — only the counts above.

Routes

  • IV/IO/IM 100%

United States EMS Protocol Census, n=1 protocols from 1 named agencies / 1 states, updated Sep 2026

Named agencies

Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.