Naloxone for Opioid overdose
Adult dosing has a median of 1 mg across 142 published protocols, with the middle half between 0.4 and 2.
1,335 rows are under review across the census and excluded from every number on this page. How that works.
Adultmg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 0.4 | 0.4 | 1 | 2 | 2 |
Values in mg. One value per source (that source's median), so a document listing a drug five times still gets one vote.
Routes
- IN 24%
- IV/IO/IM/IN 10%
- IM 10%
- IM/IN 10%
- IV 10%
- IV/IO 9%
- IV/IO/IM 8%
- IV/IM/IN 5%
- IV/IM 3%
- IV/IO/IM/IN/ET 3%
- IO 1%
- IV/IM/SQ 1%
- ET 1%
- IV/IO/ET 1%
- IV/IO/IN 1%
- NEB 1%
- SQ 1%
- IM/SQ 0%
- IV/IN 0%
- IV/IO/IM/IN/NEB 0%
- IV/IO/IM/IN/SL/ET 0%
- IV/IO/IM/SQ/NEB 0%
United States EMS Protocol Census, n=142 protocols from 122 named agencies / 32 states, updated Sep 2026
Pediatric, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 0.1 | 0.1 | 0.1 | 0.1 | 0.15 |
Values in mg/kg. One value per source (that source's median), so a document listing a drug five times still gets one vote.
Routes
- IN 22%
- IM/IN 12%
- IV/IO/IM 12%
- IV/IO 10%
- IV/IO/IM/IN 9%
- IV 8%
- IM 7%
- IV/IM/IN 6%
- IV/IM 5%
- IV/IO/IM/IN/ET 4%
- IV/IM/SQ 1%
- IV/IO/ET 1%
- IO 1%
- IV/IN 1%
- IV/IO/IM/IN/NEB 1%
- IV/IO/IM/IN/SL/ET 1%
United States EMS Protocol Census, n=96 protocols from 87 named agencies / 26 states, updated Sep 2026
Pediatricmg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 0.4 | 0.5 | 1 | 2 | 2 |
Values in mg. One value per source (that source's median), so a document listing a drug five times still gets one vote.
Routes
- IN 42%
- IV/IO/IM/IN 18%
- IM 12%
- IM/IN 6%
- IV/IM/IN 6%
- IV/IM 3%
- IV/IO 3%
- IV/IO/IN 3%
- NEB 3%
- SQ 3%
United States EMS Protocol Census, n=24 protocols from 18 named agencies / 15 states, updated Sep 2026
Adult, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
Values in mg/kg. One value per source (that source's median), so a document listing a drug five times still gets one vote.
Routes
- IN 20%
- IV/IO/IM/IN 20%
- IV/IO/IM/IN/ET 20%
- IM 10%
- IV 10%
- IV/IM/IN 10%
United States EMS Protocol Census, n=7 protocols from 6 named agencies / 6 states, updated Sep 2026
PediatricmL
Below 5 sources, so no distribution is published for this group — only the counts above.
Routes
- IN 100%
United States EMS Protocol Census, n=1 protocols from 1 named agencies / 1 states, updated Sep 2026
Named agencies
Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.
- Ada County-City Emergency Services System
- Adams, Benton, Franklin, Yakima Counties
- Adams, Benton, Franklin, Yakima Counties EMS
- Anderson County Emergency Medical Services
- Arlington EMS System
- Ascension Saint Joseph Hospital EMS System
- BC Emergency Health Services
- Berrien County
- Berrien County Medical Control Authority
- BEST EMS
- Bexar County ESD 4 Fire Rescue
- Boulder County EMS
- Boulder County Protocol Committee
- Brigham City, Cache County, Logan City, Smithfield Fire Departments
- Brilliant Fire Department
- Brunswick County EMS
- Bureau of EMS, Trauma & Preparedness
- Cabarrus County EMS
- Campbell County Emergency Medical Service
- Central Arizona Regional EMS
- Central California Emergency Medical Services
- Chelan/Douglas/Okanogan/Grant County
- City of Austin
- City of Austin / Austin-Travis County EMS System
- City of Austin Office of the Chief Medical Officer
- Cochran County Emergency Medical Services
- County of Marin EMS
- County of Riverside Emergency Medical Services Agency
- County of Riverside Emergency Medical Services (EMS) Agency (REMSA)
- County of San Diego Emergency Medical Services
- Craven, Jones, Pamlico Counties EMS
- Crowley Fire Department
- Davidson County Emergency Services
- Daviess County EMS
- Delaware Office of Emergency Medical Services
- Denver Health Paramedic Division
- Denver Metro EMS Medical Directors
- Department of Health Services, County of Los Angeles
- District of Columbia Fire and EMS Department
- Dorchester County EMS
- Evansville Fire Department
- Fairfax County Fire and Rescue Department
- Fern Creek Fire and Emergency Medical Services
- Fort Lauderdale Fire Rescue
- Galveston Area Ambulance Authority
- Giles County EMS
- Greater Miami Valley EMS Council
- Hays County ESD 9 EMS
- Haywood County EMS System
- Houston Fire Department
- Hunt County EMS
- Inland Counties Emergency Medical Agency
- Kentucky Board of Emergency Medical Services
- Kern County Public Health
- Kershaw County Emergency Medical Services
- Lake Cities Fire Department
- Lake County Emergency Medical System
- Laurens County Emergency Medical Services
- Manatee County Emergency Medical Services
- Marin County Emergency Medical Services Agency
- Massachusetts Department of Public Health, Office of Emergency Medical Services
- Massachusetts Office of Emergency Medical Services
- Mecklenburg EMS Agency
- MEP (In partnership with SSM Health)
- MEP (Medical Emergency Partnership) in partnership with SSM Health
- Metro Regional EMS
- Metro Regional EMS Consortium
- Michigan Department of Health and Human Services (MDHHS)
- Michigan Department of Health and Human Services (MDHHS) / Berrien County
- Michigan Department of Health and Human Services (MDHHS) / Midland Gladwin MCA
- Michigan Department of Health and Human Services (MDHHS) / West Michigan Regional MCC
- Michigan Department of Health & Human Services, Bureau of Emergency Preparedness, EMS and Systems of Care
- Ministry of Health, Emergency Health Regulatory and Accountability Branch
- Miramar Fire Rescue Department
- Muskegon County
- Nash County Emergency Medical Services
- New Hampshire Bureau of Emergency Medical Services
- New Jersey Department of Health
- New York State Department of Health, Bureau of Emergency Medical Services and Trauma Systems
- North Carolina Office of Emergency Medical Services (NC OEMS)
- Northwest Community EMS System
- Northwest Region Emergency Medical Services & Trauma Care Council
- Oakland County Medical Control Authority
- Oakland County Medical Control Authority (OCMCA)
- Ocala/Marion County/The Villages Public Safety EMS
- Office of the EMS Medical Director for Kansas City, Missouri
- Old Dominion EMS Alliance, Inc.
- Pend Oreille County Emergency Medical Services
- Pennsylvania Department of Health, Bureau of Emergency Medical Services
- Pettis County Ambulance District
- Pierce County Emergency Medical Services
- Platte Valley Ambulance Service
- Region 4 EMS (Alton Memorial Hospital, Anderson Hospital, HSHS St. Elizabeth's Hospital, OSF St. Anthony's Health Center)
- Region One Metropolitan Ambulance Council (MAC)
- Regional Emergency Medical Advisory Committee of New York City
- Richland County Emergency Medical Services
- Riverside County Emergency Medical Services Agency (REMSA)
- Rowan County Emergency Services EMS Division
- Salt Lake County EMS
- San Diego County Emergency Medical Services Office
- Santa Barbara County Public Health Department
- Seattle and King County EMS
- South Plains Emergency Medical Services
- Southern Fox Valley EMS System
- St. Johns County Fire Rescue
- Stanislaus County Emergency Medical Services Agency
- Stanly County EMS
- State Board of Emergency Medical, Fire, and Transportation Services
- State Board of Emergency Medical, Fire, and Transportation Services (EMFTS Board)
- Stevens County Emergency Medical Services
- Susquehanna Regional EMS
- Tennessee Emergency Medical Services
- The Williamson County EMS System
- Three Rivers Ambulance Authority & Fort Wayne Fire Department
- Thurston County Medic One
- Tidewater Emergency Medical Services Council, Inc.
- Tri County Emergency Medical Services, Inc.
- Utah Department of Public Safety, Bureau of Emergency Medical Services
- Washington State Department of Health
- West Palm Beach Fire Department