Diphenhydramine for Allergic reaction
Adult dosing has a median of 37.5 mg across 115 published protocols, with the middle half between 25 and 50.
1,335 rows are under review across the census and excluded from every number on this page. How that works.
Adultmg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 12.5 | 25 | 37.5 | 50 | 50 |
Values in mg. One value per source (that source's median), so a document listing a drug five times still gets one vote.
Routes
- IV/IO/IM 31%
- IV/IM 19%
- PO 17%
- IM 8%
- IV/IO/IM/PO 8%
- IV 6%
- IV/IM/PO 5%
- IV/IO 4%
- IO/IM 1%
- IV/PO 1%
United States EMS Protocol Census, n=115 protocols from 105 named agencies / 34 states, updated Sep 2026
Pediatric, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 0.5 | 1 | 1 | 1 | 1.5 |
Values in mg/kg. One value per source (that source's median), so a document listing a drug five times still gets one vote.
Routes
- IV/IO/IM 29%
- IV/IM 21%
- PO 16%
- IM 10%
- IV 8%
- IV/IO/IM/PO 7%
- IV/IM/PO 4%
- IV/IO 4%
- IO/IM 1%
- IV/PO 1%
United States EMS Protocol Census, n=106 protocols from 98 named agencies / 32 states, updated Sep 2026
Adult, weight-basedmg/kg
| min | p25 | median | p75 | max |
|---|---|---|---|---|
| 1 | 1 | 1 | 1 | 1 |
Values in mg/kg. One value per source (that source's median), so a document listing a drug five times still gets one vote.
Routes
- IV/IM 23%
- PO 23%
- IM 14%
- IV 14%
- IV/IO/IM/PO 14%
- IV/IO/IM 9%
- IV/IM/PO 5%
United States EMS Protocol Census, n=14 protocols from 13 named agencies / 10 states, updated Sep 2026
Pediatricmg
Below 5 sources, so no distribution is published for this group — only the counts above.
Routes
- PO 100%
United States EMS Protocol Census, n=2 protocols from 2 named agencies / 2 states, updated Sep 2026
Named agencies
Agencies whose protocols are a public record are named here. Their own doses are on their own pages; this list carries no values.
- Adams, Benton, Franklin, Yakima Counties
- Adams, Benton, Franklin, Yakima Counties EMS
- Alabama Department of Public Health (ADPH) Office of EMS (OEMS)
- Alabama Department of Public Health Office of Emergency Medical Services
- Anderson County Emergency Medical Services
- Arlington EMS System
- Ascension Saint Joseph Hospital EMS System
- Berrien County Medical Control Authority
- BEST EMS
- Bexar County ESD 4 Fire Rescue
- Boulder County Protocol Committee
- Brunswick County EMS
- Bureau of EMS, Trauma & Preparedness
- Central Arizona Regional EMS
- Central California Emergency Medical Services
- Chelan/Douglas/Okanogan/Grant County
- City of Austin
- City of Austin / Austin-Travis County EMS System
- City of Austin Office of the Chief Medical Officer
- Clark County EMS System
- Confederated Tribes of Grand Ronde Department of Emergency Services
- County of Marin EMS
- County of San Diego Emergency Medical Services
- Craven, Jones, Pamlico Counties EMS
- Crowley Fire Department
- Davidson County Emergency Services
- Daviess County EMS
- Delaware Office of Emergency Medical Services
- Denver Health Paramedic Division
- Denver Metro EMS Medical Directors
- Department of Health Services, County of Los Angeles
- District of Columbia Fire and EMS Department
- Dorchester County EMS
- Evansville Fire Department
- Fairfax County Fire and Rescue Department
- Fern Creek Fire and Emergency Medical Services
- FirstHealth of the Carolinas
- Fort Lauderdale Fire Rescue
- Franklin County Emergency Medical Services
- Giles County EMS
- Greater Miami Valley EMS Council
- Hays County ESD 9 EMS
- Haywood County EMS System
- Houston Fire Department
- Hunt County EMS
- Idaho EMS Physician Commission
- Inland Counties Emergency Medical Agency
- Kentucky Board of Emergency Medical Services
- Lake Cities Fire Department
- Lake County Emergency Medical System
- Laurens County Emergency Medical Services
- Manatee County Emergency Medical Services
- Marin County Emergency Medical Services Agency
- Maryland Institute for Emergency Medical Services Systems
- Mecklenburg EMS Agency
- MEP (Medical Emergency Partnership) in partnership with SSM Health
- Metro Regional EMS
- MetroCare Services and Abilene Fire Department
- Michigan Department of Health and Human Services (MDHHS)
- Michigan Department of Health and Human Services (MDHHS) / Berrien County
- Michigan Department of Health and Human Services (MDHHS) / West Michigan Regional MCC
- Miramar Fire Rescue Department
- Muskegon County
- Muskogee County EMS
- National Emergency Medical Services
- Nebraska Board of Emergency Medical Services
- Nebraska Medicine Division of Prehospital and Emergency Medical Services
- New Jersey Department of Health
- New York State Department of Health, Bureau of Emergency Medical Services and Trauma Systems
- North Carolina Office of Emergency Medical Services (NC OEMS)
- Northwest Community EMS System
- Northwest Region Emergency Medical Services & Trauma Care Council
- Oakland County Medical Control Authority
- Oakland County Medical Control Authority (OCMCA)
- Ocala/Marion County/The Villages Public Safety EMS
- Old Dominion EMS Alliance, Inc.
- Pend Oreille County Emergency Medical Services
- Peninsulas EMS Council, Inc.
- Pennsylvania Department of Health, Bureau of Emergency Medical Services
- Pierce County Emergency Medical Services
- Platte Valley Ambulance Service
- Region 4 EMS (Alton Memorial Hospital, Anderson Hospital, HSHS St. Elizabeth's Hospital, OSF St. Anthony's Health Center)
- Region One Metropolitan Ambulance Council (MAC)
- Region X EMS
- Richland County Emergency Medical Services
- Rowan County Emergency Services EMS Division
- San Diego County Emergency Medical Services Office
- Santa Barbara County Public Health Department
- South Plains Emergency Medical Services
- Southern Fox Valley EMS System
- Spokane County EMS
- St. Johns County Fire Rescue
- Stanislaus County Emergency Medical Services Agency
- Stanly County EMS
- State Board of Emergency Medical, Fire, and Transportation Services
- State Board of Emergency Medical, Fire, and Transportation Services (EMFTS Board)
- Stevens County Emergency Medical Services
- Susquehanna Regional EMS
- Three Rivers Ambulance Authority & Fort Wayne Fire Department
- Thurston County Medic One
- Tidewater Emergency Medical Services Council, Inc.
- Vermont Department of Health, Office of Emergency Medical Services
- Washington State Department of Health
- West Virginia Department of Health, Office of Emergency Medical Services
- Wilson County Emergency Management Agency